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SYNTHETIC BIOLOGY

January 25, 2020 by sbrand


Capabilities and Facilities

The Joint Genome Institute: A DOE User Facility for Genomics-enabled Discovery (LBNL, LLNL)

The Agile BioFoundry: Advanced Tools, Analytics, and Rapid Engineering of Production Microbes (LBNL, SNL, PNNL, NREL, LANL, ORNL, ANL)

Structural Biology and Imaging Resources at Synchrotron and Neutron Facilities (ANL, BNL, LBNL, ORNL, SLAC)

Environmental Molecular Sciences Laboratory (PNNL)

EDGE Bioinformatics: Next Generation Sequencing for Exploring Genomes and Metagenomes (LANL)

National Microbiome Data Collaborative: Microbiome Data Catalog to Enable Discovery and Applications for Energy, Agriculture, Health and Environments (LBNL, LANL, ORNL, PNNL)

KBase: The U.S. Department of Energy Systems Biology Knowledgebase (LBNL, ANL, ORNL)


Software and Tools

CRISPR/Cas9 RNA Editing (SNL)

ART: A Machine Learning Recommendation Tool for Guiding Synthetic Biology (LBNL)

Bacterial Quantitative Trait-Locus Mapping (ORNL

FeatureCreature: An OSS Tool for Structural Visualization of Machine-learned Quantitative Structure Activity Relationships (QSARs) Explanations (SNL)

Jungle Express: Efficient Gene Expression at Negligible Cost (LBNL)

TNT Digestion-Ligation Buffer Formulation (ORNL)

CRAGE: Chassis-independent Recombinase-assisted Genome Engineering: A Universal Approach to Engineer Pathways in a Broad Range of Bacteria (LBNL)

Novel Fungal Auto-inducible Expression System (LBNL)

MAGI: Metabolite, Annotation, and Gene Integration System (LBNL)

BOOST: Build-optimization Software Tools for Redesigning Difficult Nucleotide Sequences for DNA Synthesis (LBNL)

Arrowland: A Multiscale Interactive Tool for Omics Data Visualization (LBNL, SNL)


Microbial and Plant Engineering

Engineered Microbes for Plastic Degradation and Upcycling (NREL)

Transformable Rhodobacter Strains, Method for Producing Transformable Rhodobacter Strains (ANL)

Engineered Photosynthetic Bacteria, Method of Manufacture of Biofuels (ANL)

Creating Synthetic Microbial Consortia (PNNL)

Method and Strain for Sugar Conversion (ORNL)

Synthetic Promoters Useful for Expression in Plant Cells (LBNL)

Agrobacterium-mediated Transformation of Lipomyces (PNNL)

Novel Genes Controlling Cell Wall Biosynthesis (ORNL)

Nanoengineered Membranes for Controlled Transport (ORNL)

Conserved Function between Human and Plant (ORNL)

Fatty Alcohols from Engineered Yeast (LBNL)

Alkyl Lactones from Hydroxy Fatty Acids (LBNL)


Participating DOE laboratories and contact information

ANL Argonne National Laboratory
Phil Smith, PESmith@anl.gov

BNL Brookhaven National Laboratory
Poornima Upadhya, PUpadhya@bnl.gov

INL Idaho National Laboratory
Ryan Bills, Ryan.Bills@inl.gov

LBNL Lawrence Berkeley National Laboratory
Robin Johnston, RJohnston@lbl.gov

LLNL Lawrence Livermore National Laboratory
Hannah Farquar, farquar3@llnl.gov

LANL Los Alamos National Laboratory
Marc Steven Witkowski, Witk@lanl.gov

NREL National Renewable Energy Laboratory
Eric Payne, Eric.Payne@nrel.gov

ORNL Oak Ridge National Laboratory
Jennifer Caldwell, CaldwellJT@ornl.gov

PNNL Pacific Northwest National Laboratory
Allan Tuan, Allan.Tuan@pnnl.gov

SNL Sandia National Laboratory
Joel Sikora, JSikora@sandia.gov

These technologies can also be found at the DOE Lab Partnering Service

Filed Under: Tech Expo